Table of Contents - *180473
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Genome
DNA
Protein
Gene Info
Variation
Animal Models
Cellular Pathways
| *180473 | ||||||||
| RIBOSOMAL PROTEIN S18; RPS18 | ||||||||
| HGNC Approved Gene Symbol: RPS18 | ||||||||
| Cytogenetic location: 6p21.32 Genomic coordinates (GRCh37): 6:33,239,851 - 33,244,280 (from NCBI) | ||||||||
| TEXT | ||||||||
| The mammalian ribosome is composed of 4 RNA species (see 180450) and approximately 80 different proteins. In a search for new genes preferentially expressed in cytotrophoblasts of first-trimester human placenta, Chassin et al. (1993) made a subtracted cDNA library and found clones with an open reading frame showing a sequence that predicted a protein with 100% amino acid homology to the mouse ke3 gene product. The Ke3 gene in the mouse is located in the major histocompatibility complex. The deduced RPS18 protein has 152 amino acids (SWISS-PROT P25232). In their GenBank submission (X69150), Chassin et al. (1993) noted that the RPS18 gene maps to 6p21.3. Kenmochi et al. (1998) mapped the RPS18 gene to 6p using somatic cell hybrid and radiation hybrid mapping analyses. | ||||||||
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