- Fine hair (HP:0002213): Hair that is fine or thin to the touch. Evidence: PCS. (PMID:18231121)
- Heat intolerance (HP:0002046): The inability to maintain a comfortable body temperature in warm or hot weather. Evidence: PCS. Frequency: 1/10. (PMID:18231121)
- Microdontia (HP:0000691): Decreased size of the teeth, which can be defined as a mesiodistal tooth diameter (width) more than 2 SD below mean. Alternatively, an apparently decreased maximum width of tooth. Evidence: IEA. (OMIM:129490)
- Sparse eyebrow (HP:0045075): Decreased density/number of eyebrow hairs. Evidence: PCS. Frequency: 8/10. (PMID:18231121)
- Sparse hair (HP:0008070): Reduced density of hairs. Evidence: PCS. (PMID:18231121)
- Dry skin (HP:0000958): Skin characterized by the lack of natural or normal moisture. Evidence: PCS. (PMID:18231121)
- Ectodermal dysplasia (HP:0000968): Ectodermal dysplasia is a group of conditions in which there is abnormal development of the skin, hair, nails, teeth, or sweat glands. Evidence: PCS. (PMID:18231121)
- Ridged nail (HP:0001807): Longitudinal, linear prominences in the nail plate. Evidence: PCS. Frequency: 1/10. (PMID:18231121)
- Hypodontia (HP:0000668): The absence of five or less teeth from the normal series by a failure to develop. Evidence: PCS. Frequency: 2/10. (PMID:18231121)
- Hypohidrosis (HP:0000966): Abnormally diminished capacity to sweat. Evidence: PCS. Frequency: 10/10. (PMID:18231121)
- Sparse eyelashes (HP:0000653): Decreased density/number of eyelashes. Evidence: PCS. (PMID:18231121)
- Anodontia (HP:0000674): The absence of all teeth from the normal series by a failure to develop. Evidence: IEA. (OMIM:129490)
- Slow-growing hair (HP:0002217): Hair whose growth is slower than normal. Evidence: IEA. (OMIM:129490)
- Autosomal dominant inheritance (HP:0000006): A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in heterozygotes. In the context of medical genetics, an autosomal dominant disorder is caused when a single copy of the mutant allele is present. Males and females are affected equally, and can both transmit the disorder with a risk of 50% for each child of inheriting the mutant allele. Evidence: PCS. (PMID:10431241)
These phenotypes are associated with the disease ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant (OMIM:129490).