- Elevated circulating luteinizing hormone level (HP:0011969): An elevated concentration of luteinizing hormone in the blood. Evidence: PCS. Frequency: 1/7. (PMID:33963445)
- Male infertility (HP:0003251). Evidence: PCS. Frequency: 7/7. (PMID:33963445)
- Young adult onset (HP:0011462): Onset of disease at the age of between 16 and 40 years. Evidence: PCS. Frequency: 7/7. (PMID:33963445)
- Elevated circulating follicle stimulating hormone level (HP:0008232): An elevated concentration of follicle-stimulating hormone in the blood. Evidence: PCS. Frequency: 5/7. (PMID:33963445)
- Decreased serum testosterone concentration (HP:0040171). Evidence: PCS. Frequency: 3/7. (PMID:33963445)
- Abnormal prolactin level (HP:0040086). Evidence: PCS. Frequency: 0/7. (PMID:33963445)
- X-linked inheritance (HP:0001417): A mode of inheritance that is observed for traits related to a gene encoded on the X chromosome. Evidence: PCS. (PMID:33963445)
- Azoospermia (HP:0000027): Absence of any measurable level of sperm,whereby spermatozoa cannot be observed even after centrifugation of the semen pellet. Evidence: PCS. Frequency: 5/7. (PMID:33963445)
These phenotypes are associated with the disease spermatogenic failure, X-linked, 4 (OMIM:301077).