Entry - *601670 - D4, ZINC, AND DOUBLE PHD FINGERS FAMILY, MEMBER 1; DPF1 - OMIM

 
 
* 601670

D4, ZINC, AND DOUBLE PHD FINGERS FAMILY, MEMBER 1; DPF1


Alternative titles; symbols

NEURO-D4, RAT, HOMOLOG OF; NEUD4
BRG1-ASSOCIATED FACTOR, 45-KD, B; BAF45B


HGNC Approved Gene Symbol: DPF1

Cytogenetic location: 19q13.2   Genomic coordinates (GRCh38) : 19:38,211,006-38,229,695 (from NCBI)


TEXT

▼ Cloning and Expression

Chestkov et al. (1996) described human DPF1, which they called Neuro-D4, a conserved gene encoding a 353-amino acid neural-specific zinc finger protein. A cysteine- and histidine-rich region of the C terminus distinguishes members of the D4 family, including Neuro-D4, from other zinc finger proteins. The human and rat Neuro-D4 cDNAs are 93% identical, and there are only 3 amino acid differences between the proteins. Different alternatively spliced cDNAs were observed.


▼ Mapping

Chestkov et al. (1996) mapped the DPF1 gene to chromosome 19 by somatic cell hybrid analysis.


▼ REFERENCES

  1. Chestkov, A. V., Baka, I. D., Kost, M. V., Georgiev, G. P., Buchman, V. L. The d4 gene family in the human genome. Genomics 36: 174-177, 1996. [PubMed: 8812431, related citations] [Full Text]


Creation Date:
Alan F. Scott : 2/7/1997
Edit History:
mgross : 10/05/2009
mgross : 11/20/2008
mgross : 11/20/2008
jenny : 2/11/1997
jenny : 2/7/1997

* 601670

D4, ZINC, AND DOUBLE PHD FINGERS FAMILY, MEMBER 1; DPF1


Alternative titles; symbols

NEURO-D4, RAT, HOMOLOG OF; NEUD4
BRG1-ASSOCIATED FACTOR, 45-KD, B; BAF45B


HGNC Approved Gene Symbol: DPF1

Cytogenetic location: 19q13.2   Genomic coordinates (GRCh38) : 19:38,211,006-38,229,695 (from NCBI)


TEXT

Cloning and Expression

Chestkov et al. (1996) described human DPF1, which they called Neuro-D4, a conserved gene encoding a 353-amino acid neural-specific zinc finger protein. A cysteine- and histidine-rich region of the C terminus distinguishes members of the D4 family, including Neuro-D4, from other zinc finger proteins. The human and rat Neuro-D4 cDNAs are 93% identical, and there are only 3 amino acid differences between the proteins. Different alternatively spliced cDNAs were observed.


Mapping

Chestkov et al. (1996) mapped the DPF1 gene to chromosome 19 by somatic cell hybrid analysis.


REFERENCES

  1. Chestkov, A. V., Baka, I. D., Kost, M. V., Georgiev, G. P., Buchman, V. L. The d4 gene family in the human genome. Genomics 36: 174-177, 1996. [PubMed: 8812431] [Full Text: https://doi.org/10.1006/geno.1996.0440]


Creation Date:
Alan F. Scott : 2/7/1997

Edit History:
mgross : 10/05/2009
mgross : 11/20/2008
mgross : 11/20/2008
jenny : 2/11/1997
jenny : 2/7/1997



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: Nov. 16, 2024