Entry - *602386 - ZINC FINGER PROTEIN 212; ZNF212 - OMIM

 
 
* 602386

ZINC FINGER PROTEIN 212; ZNF212


Alternative titles; symbols

ZINC FINGER PROTEIN C2H2-150


HGNC Approved Gene Symbol: ZNF212

Cytogenetic location: 7q36.1   Genomic coordinates (GRCh38) : 7:149,239,651-149,255,606 (from NCBI)


TEXT

▼ Description

Zinc finger proteins (ZNFs), which bind nucleic acids, perform many key functions, the most important of which is regulating transcription. See ZNF91 (603971) for general information on ZNFs.

▼ Cloning and Expression

Becker et al. (1997) reported the cloning of a C2H2-type, or Kruppel-related (see 602187), zinc finger protein from a human hippocampus cDNA library. The partial cDNA, designated C2H2-150, encodes a predicted 356-amino acid protein, with 4 C-terminal C2H2 zinc finger motifs and an N-terminal Kruppel-associated box (KRAB).


▼ Mapping

By PCR of somatic cell hybrids, Becker et al. (1997) mapped the gene encoding C2H2-150 to 7q36.1.


▼ REFERENCES

  1. Becker, K. G., Nagle, J. W., Canning, R. D., Dehejia, A. M., Polymeropoulos, M. H., Gado, A. M., Biddison, W. E., Drew, P. D. Molecular cloning and mapping of a novel human KRAB domain-containing C2H2-type zinc finger to chromosome 7q36.1. Genomics 41: 502-504, 1997. [PubMed: 9169157, related citations] [Full Text]


Creation Date:
Rebekah S. Rasooly : 2/24/1998
Edit History:
carol : 12/22/2006
carol : 2/18/2002
carol : 9/27/1999
alopez : 2/24/1998

* 602386

ZINC FINGER PROTEIN 212; ZNF212


Alternative titles; symbols

ZINC FINGER PROTEIN C2H2-150


HGNC Approved Gene Symbol: ZNF212

Cytogenetic location: 7q36.1   Genomic coordinates (GRCh38) : 7:149,239,651-149,255,606 (from NCBI)


TEXT

Description

Zinc finger proteins (ZNFs), which bind nucleic acids, perform many key functions, the most important of which is regulating transcription. See ZNF91 (603971) for general information on ZNFs.

Cloning and Expression

Becker et al. (1997) reported the cloning of a C2H2-type, or Kruppel-related (see 602187), zinc finger protein from a human hippocampus cDNA library. The partial cDNA, designated C2H2-150, encodes a predicted 356-amino acid protein, with 4 C-terminal C2H2 zinc finger motifs and an N-terminal Kruppel-associated box (KRAB).


Mapping

By PCR of somatic cell hybrids, Becker et al. (1997) mapped the gene encoding C2H2-150 to 7q36.1.


REFERENCES

  1. Becker, K. G., Nagle, J. W., Canning, R. D., Dehejia, A. M., Polymeropoulos, M. H., Gado, A. M., Biddison, W. E., Drew, P. D. Molecular cloning and mapping of a novel human KRAB domain-containing C2H2-type zinc finger to chromosome 7q36.1. Genomics 41: 502-504, 1997. [PubMed: 9169157] [Full Text: https://doi.org/10.1006/geno.1997.4678]


Creation Date:
Rebekah S. Rasooly : 2/24/1998

Edit History:
carol : 12/22/2006
carol : 2/18/2002
carol : 9/27/1999
alopez : 2/24/1998



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: Nov. 17, 2024