Entry - *602946 - TAF6-LIKE RNA POLYMERASE II; TAF6L - OMIM

 
 
* 602946

TAF6-LIKE RNA POLYMERASE II; TAF6L


Alternative titles; symbols

PCAF-ASSOCIATED FACTOR 65 ALPHA; PAF65A
PCAF-ASSOCIATED FACTOR, 65-KD


HGNC Approved Gene Symbol: TAF6L

Cytogenetic location: 11q12.3   Genomic coordinates (GRCh38) : 11:62,771,396-62,787,342 (from NCBI)


TEXT

▼ Cloning and Expression

Ogryzko et al. (1998) identified the human polypeptide PAF65A as a subunit of the PCAF complex (see 602303). PAF65A shows sequence similarity to human TAFII80 (602955). The predicted 622-amino acid protein contains a histone H4-like region (residues 12-86).


▼ Gene Function

Struhl and Moqtaderi (1998) reviewed the potential roles of the PCAF complex in transcription.


▼ Mapping

Hartz (2009) mapped the TAF6L gene to chromosome 11q12.3 based on an alignment of the TAF6L sequence (GenBank AF069735) with the genomic sequence (GRCh37).

▼ REFERENCES

  1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/8/2009.

  2. Ogryzko, V. V., Kotani, T., Zhang, X., Schiltz, R. L., Howard, T., Yang, X.-J., Howard, B. H., Qin, J., Nakatani, Y. Histone-like TAFs within the PCAF histone acetylase complex. Cell 94: 35-44, 1998. [PubMed: 9674425, related citations] [Full Text]

  3. Struhl, K., Moqtaderi, Z. The TAFs in the HAT. Cell 94: 1-4, 1998. [PubMed: 9674419, related citations] [Full Text]


Creation Date:
Stylianos E. Antonarakis : 8/6/1998
Edit History:
terry : 12/09/2009
carol : 12/8/2009
carol : 12/5/2001
carol : 8/24/1998
carol : 8/6/1998

* 602946

TAF6-LIKE RNA POLYMERASE II; TAF6L


Alternative titles; symbols

PCAF-ASSOCIATED FACTOR 65 ALPHA; PAF65A
PCAF-ASSOCIATED FACTOR, 65-KD


HGNC Approved Gene Symbol: TAF6L

Cytogenetic location: 11q12.3   Genomic coordinates (GRCh38) : 11:62,771,396-62,787,342 (from NCBI)


TEXT

Cloning and Expression

Ogryzko et al. (1998) identified the human polypeptide PAF65A as a subunit of the PCAF complex (see 602303). PAF65A shows sequence similarity to human TAFII80 (602955). The predicted 622-amino acid protein contains a histone H4-like region (residues 12-86).


Gene Function

Struhl and Moqtaderi (1998) reviewed the potential roles of the PCAF complex in transcription.


Mapping

Hartz (2009) mapped the TAF6L gene to chromosome 11q12.3 based on an alignment of the TAF6L sequence (GenBank AF069735) with the genomic sequence (GRCh37).

REFERENCES

  1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/8/2009.

  2. Ogryzko, V. V., Kotani, T., Zhang, X., Schiltz, R. L., Howard, T., Yang, X.-J., Howard, B. H., Qin, J., Nakatani, Y. Histone-like TAFs within the PCAF histone acetylase complex. Cell 94: 35-44, 1998. [PubMed: 9674425] [Full Text: https://doi.org/10.1016/s0092-8674(00)81219-2]

  3. Struhl, K., Moqtaderi, Z. The TAFs in the HAT. Cell 94: 1-4, 1998. [PubMed: 9674419] [Full Text: https://doi.org/10.1016/s0092-8674(00)81213-1]


Creation Date:
Stylianos E. Antonarakis : 8/6/1998

Edit History:
terry : 12/09/2009
carol : 12/8/2009
carol : 12/5/2001
carol : 8/24/1998
carol : 8/6/1998



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: Nov. 16, 2024