Entry - *606740 - ZINC FINGER PROTEIN 180; ZNF180 - OMIM

 
 
* 606740

ZINC FINGER PROTEIN 180; ZNF180


HGNC Approved Gene Symbol: ZNF180

Cytogenetic location: 19q13.31   Genomic coordinates (GRCh38) : 19:44,474,431-44,500,522 (from NCBI)


TEXT

▼ Description

Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See 604749 for additional information on zinc finger proteins.

▼ Cloning and Expression

By screening a human fetal heart cDNA library with a degenerate oligonucleotide based on the consensus sequence of the C2H2 zinc finger domain, Wang et al. (1996) cloned 2 novel zinc finger cDNAs, designated ZNF180 and ZNF181 (606741).


▼ Mapping

By FISH, Wang et al. (1996) mapped the ZNF180 and ZNF181 genes within a cluster of zinc finger genes on chromosome 19q13.2.


▼ REFERENCES

  1. Wang, R., Cukerman, E., Heng, H. H. Q., Liew, C.-C. Identification of a locus of zinc finger genes in human chromosome 19q13.1-q13.3 region by fluorescence in situ hybridization. Somat. Cell Molec. Genet. 22: 245-248, 1996. [PubMed: 8914611, related citations] [Full Text]


Creation Date:
Carol A. Bocchini : 3/1/2002
Edit History:
terry : 03/01/2002
carol : 3/1/2002

* 606740

ZINC FINGER PROTEIN 180; ZNF180


HGNC Approved Gene Symbol: ZNF180

Cytogenetic location: 19q13.31   Genomic coordinates (GRCh38) : 19:44,474,431-44,500,522 (from NCBI)


TEXT

Description

Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See 604749 for additional information on zinc finger proteins.

Cloning and Expression

By screening a human fetal heart cDNA library with a degenerate oligonucleotide based on the consensus sequence of the C2H2 zinc finger domain, Wang et al. (1996) cloned 2 novel zinc finger cDNAs, designated ZNF180 and ZNF181 (606741).


Mapping

By FISH, Wang et al. (1996) mapped the ZNF180 and ZNF181 genes within a cluster of zinc finger genes on chromosome 19q13.2.


REFERENCES

  1. Wang, R., Cukerman, E., Heng, H. H. Q., Liew, C.-C. Identification of a locus of zinc finger genes in human chromosome 19q13.1-q13.3 region by fluorescence in situ hybridization. Somat. Cell Molec. Genet. 22: 245-248, 1996. [PubMed: 8914611] [Full Text: https://doi.org/10.1007/BF02369916]


Creation Date:
Carol A. Bocchini : 3/1/2002

Edit History:
terry : 03/01/2002
carol : 3/1/2002



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: Nov. 17, 2024